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tag next gen sequencing circadian clocks reproducibility

A Nile rat sitting atop fruits
Genome Spotlight: Nile Rat (Avicanthis niloticus)
Christie Wilcox, PhD | Nov 23, 2022 | 4 min read
A reference sequence for this emerging model organism will facilitate research on type 2 diabetes and the health effects of circadian rhythm disruption.
Tagged for Cleansing
Michele Pagano | Jun 1, 2009 | 10+ min read
Tagged for Cleansing Not just the cell's trash and recycling center, the ubiquitin system controls complex cellular pathways with elegant simplicity and precision. By Michele Pagano have always gravitated toward order. I may even take it a bit too far according to friends who liken my office to a museum. However, I like to think it not a compulsion, but a Feng Shui approach to life. With this need for order, I may have been better suited to
Robots Toil Round The Clock In Today's Science Laboratories
Rebecca Andrews | May 12, 1991 | 7 min read
It is 2:30 in the morning at Steve Metzner's lab at Monsanto Co. in St. Louis, and lab workers are busy preparing samples for an experiment to be run that day. These workers aren't diligent technicians, however--they're robots, and they're freeing the laboratory's human workers to do more complicated and challenging tasks when they arrive. To the functioning of Metzner's lab, and many others around the United States, robotics has become integral. While most prevalent in labs that perform highly
How Time Is Encoded in Memories
Catherine Offord | May 1, 2020 | 10+ min read
Rats and equations help researchers develop a theory of how our brains keep track of when events took place.
One Step Beyond: Going Beyond Genomics With Proteomics And Two-Dimensional Gel Technology
Laura Defrancesco | Jan 3, 1999 | 10+ min read
Proteomes and 2D Gel Apparatus Providers Big science has moved on to proteins. With the new brand of science termed proteomics--named by the Australians Marc Wilkins and Keith Williams to mean the "set of PROTEins encoded by the genOME"--the push is on around the globe to produce a complete description of a cell/tissue/organism in terms of the proteins produced. The challenge is all the greater because the expressed protein pattern changes with time and environment--responding to developmenta
Southbound genes
Amber Dance | Apr 7, 2009 | 3 min read
A genome study in monarch butterflies pulls out a set of 40 key players in long distance migration
Decoding DNA: New Twists and Turns
Kerry Grens | Jun 1, 2013 | 10+ min read
Highlights from a series of three webinars on the future of genome research, held by The Scientist to celebrate 60 years of the DNA double helix
On the Chain Gang
Keith D. Wilkinson and David Fushman | Jul 1, 2012 | 10 min read
More than simply helping haul out a cell’s garbage, ubiquitin, with its panoply of chain lengths and shapes, marks and regulates many unrelated cellular processes.
Top Ten Innovations 2011
The Scientist | Jan 1, 2012 | 10+ min read
Our list of the best and brightest products that 2011 had to offer the life scientist
Differential Gene Expression: Technology Provides Quick Access to DNA Data
James Kling | Aug 30, 1998 | 6 min read
HOW IT WORKS: This diagram shows how Genzyme's SAGE method flows from one stage to another. In 1997, Genzyme Corp. of Cambridge, Mass., was shopping for new technology. "We were creating a cancer company, to put together a group of technologies that would give us a gene-based approach to cancer drug discovery," recalls Susan Primrose, director of business development at the now-formed Genzyme Molecular Oncology (GMO) in Framingham, Mass. They found a key to their project in SAGE (Serial Anal

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