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image: Disease-Linked Genes Questioned

Disease-Linked Genes Questioned

By Jef Akst | January 6, 2016

Many patients with genetic variations linked to cardiac disorders do not exhibit any symptoms, raising concerns about the validity of incidental findings of genetic tests.

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image: TS Picks: CRISPR Patent Edition

TS Picks: CRISPR Patent Edition

By Kerry Grens | January 5, 2016

A challenge to the first CRISPR patent just got teeth.

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image: Molecular Fingerprint Predicts Flu Shot Response

Molecular Fingerprint Predicts Flu Shot Response

By Jyoti Madhusoodanan | January 4, 2016

A gene-expression signature correlates with a person’s likelihood of experiencing adverse events after receiving a seasonal flu vaccine, scientists show. 

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image: Updating the Polio Vaccine

Updating the Polio Vaccine

By Jef Akst | January 4, 2016

Researchers develop new attenuated viruses that could support the eradication effort.

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image: CRISPR Improves Disease in Adult Mice

CRISPR Improves Disease in Adult Mice

By Kerry Grens | January 4, 2016

Three groups of researchers used the gene-editing method to restore a protein deficient in Duchenne muscular dystrophy.

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image: Pluripotency Bots

Pluripotency Bots

By Kate Yandell | January 1, 2016

A tour of efforts to automate the production and differentiation of induced pluripotent stem cells

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image: All Together Now

All Together Now

By Mary Beth Aberlin | January 1, 2016

Understanding the biological roots of cooperation might help resolve some of the biggest scientific challenges we face.

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image: Contributors

Contributors

By Karen Zusi | January 1, 2016

Meet some of the people featured in the January 2016 issue of The Scientist.

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image: Managing Methylation

Managing Methylation

By Karen Zusi | January 1, 2016

A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.

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image: Picking Up the Pace

Picking Up the Pace

By Kate Yandell | January 1, 2016

FDA designations promise to expedite the approval of drugs for conditions ranging from infectious disease to cancer.

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