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image: The Role of DNA Base Modifications

The Role of DNA Base Modifications

By | September 1, 2017

Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.

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image: Dengue Infection Impairs Immune Defense Against Zika

Dengue Infection Impairs Immune Defense Against Zika

By | August 18, 2017

A memory B cell response to Zika virus in dengue-infected patients produced antibodies that were poorly neutralizing in vitro and instead enhanced infection.

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image: The Ever-Expanding T-Cell World: A Primer

The Ever-Expanding T-Cell World: A Primer

By | August 7, 2017

Researchers continue to identify new T-cell subtypes—and devise ways to use them to fight cancer. The Scientist attempts to catalog them all.

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image: Fascinated by Folding

Fascinated by Folding

By | August 4, 2017

Lila Gierasch uses biochemical tools to understand how linear chains of amino acids turn into complex three-dimensional structures.

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A new method stimulates B cells to make human antigen-specific antibodies, obviating the need for vaccinating blood donors or hunting for rare B cells.

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Another case of HIV remission emerges, this time in a South African girl diagnosed as an infant and disease-free for more than eight years.

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image: Mammalian Immunity: What’s RNAi Got to Do with It?

Mammalian Immunity: What’s RNAi Got to Do with It?

By | July 21, 2017

A new study adds to the evidence that mammalian cells can use small interfering RNAs to defend against viruses, but questions remain about physiological importance.

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Using single-cell RNA sequencing, scientists characterize new populations of dendritic cells and monocytes.

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The presence of similar light-emitting enzymes in the distantly related organisms lends new insight into bioluminescence evolution.

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image: Uncovering Functions of Circular RNAs

Uncovering Functions of Circular RNAs

By | July 17, 2017

Recent research has revealed many surprises about circular RNAs, from findings that they are translated in vivo to links between their expression and disease.

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