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tag chemistry disease medicine evolution

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Directed Evolution, Phage Display Nab Chemistry Nobel
Catherine Offord and Kerry Grens | Oct 3, 2018 | 4 min read
The 2018 award goes to Frances Arnold, Gregory Winter, and George Smith.
The Chemistry of Attraction
Michelle Vettese-dadey | Mar 5, 2000 | 6 min read
Chemokines and their receptors help direct cell migration to sites of inflammation. You heard it here--chemokine receptors and ligands are in. Inflammation, cancer, asthma, rheumatoid arthritis, angiogenesis, and AIDS are just a few areas in which chemokines and their receptors are crucial. Therefore, chemokine pathways represent potentially valuable therapeutic targets. Asthma, one of the most common chronic diseases in the industrialized world, is recognized as an inflammatory disease, and ste
Plague Genome: The Evolution Of a Pathogen
Ricki Lewis | Oct 28, 2001 | 7 min read
Plague has earned a place in history books as the Black Death of medieval Europe, and in novels, from Albert Camus' classic The Plague, to the more recent Year of Wonders.1,2 A different medium for telling the tale of the plague bacterium Yersinia pestis is its genome, recently sequenced by researchers at the Sanger Centre, the London School of Hygiene and Tropical Medicine, the Royal London School of Medicine and Dentistry, and the Imperial College of Science, Technology and Medicine.3 In addi
The Devolution of Evolution
Leonid Moroz | Nov 1, 2010 | 4 min read
By Leonid Moroz The Devolution of Evolution Why evolution and biosystematics courses must be included in all biomedical curricula. Nearly 40 years ago Theodosius Dobzhansky wrote: “Nothing in biology makes sense except in the light of evolution.” How is it, then, that so few newly minted PhDs in the biological sciences have taken any formal graduate school courses in evolution or biodiversity? This fosters a knowledge gap that can become difficult t
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
5 images related to stories highlighted in the article, including DNA strand, insect, and dog
Our Favorite Genetics Stories of 2021
Christie Wilcox, PhD | Dec 23, 2021 | 4 min read
Studies The Scientist covered this year illustrate the expanding importance of genetic and genomic research in all aspects of life science, from ecology to medicine.
High-Tech Choir Master
Karen Hopkin | Jan 1, 2012 | 8 min read
Elaine Mardis can make DNA sequencers sing, generating genome data that shed light on evolution and disease.
Contributors
The Scientist | Jun 1, 2020 | 3 min read
Meet some of the people featured in the June 2020 issue of The Scientist.

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