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image: Detecting Protein Clumps

Detecting Protein Clumps

By Ruth Williams | February 1, 2018

A synthetic genetic tool called yTRAP allows high-throughput detection of protein aggregates in cells.  

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image: Drugging the Disorderome

Drugging the Disorderome

By Amber Dance | October 1, 2017

Strategies for targeting intrinsically disordered proteins

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image: Fascinated by Folding

Fascinated by Folding

By Anna Azvolinsky | August 4, 2017

Lila Gierasch uses biochemical tools to understand how linear chains of amino acids turn into complex three-dimensional structures.

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image: Unknown Protein Structures Predicted

Unknown Protein Structures Predicted

By Ruth Williams | January 19, 2017

Metagenomic sequence data boosts the power of protein modeling software to yield hundreds of new protein structure predictions.

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Clostridium botulinum produces a transcription factor that can aggregate and self-propagate a prion-like form, leading to genome-wide changes in gene expression in E. coli, according to a study.

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image: Vlad Denic on Exploring New Fields and Failing Successfully

Vlad Denic on Exploring New Fields and Failing Successfully

By Ben Andrew Henry | December 1, 2016

The Harvard professor is pursuing fundamental questions about autophagy, protein homeostasis, and other cellular processes, and he’s always on the lookout for his next new topic.

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image: Protein Folding Pioneer Dies

Protein Folding Pioneer Dies

By Kerry Grens | October 28, 2016

Susan Lindquist of MIT and the Whitehead Institute broke scientific ground on prions and heat shock proteins.

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image: Prions in Plants?

Prions in Plants?

By Tanya Lewis | April 26, 2016

A plant protein that behaves like a prion when inserted into yeast could enable a form of botanical memory, a study suggests.

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image: Fearless about Folding

Fearless about Folding

By Anna Azvolinsky | January 1, 2016

Susan Lindquist has never shied away from letting her curiosity guide her research career.

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image: Master Folder

Master Folder

By The Scientist Staff | January 1, 2016

Meet Susan Lindquist, the MIT biologist who has won numerous accolades for her research on protein folding.

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