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tag dna repair immunology cell molecular biology

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
A Molecular Switch for Bone Loss
Mariella Bodemeier Loayza Careaga, PhD | Jan 23, 2024 | 4 min read
Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice. 
Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
3D structural model of a Cas protein and sgRNA targeting and unwinding DNA for gene editing.
CRISPR Gene Editing: Cas9 and Beyond
Johanna Pruller, PhD and Deanna MacNeil, PhD | Nov 29, 2023 | 7 min read
Researchers create and improve CRISPR-Cas mediated gene editing technologies based on prokaryotic CRISPR systems and eukaryotic DNA repair mechanisms.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
DNA repair within nucleosomes
Jonathan Weitzman(jonathanweitzman@hotmail.com) | Dec 10, 2000 | 1 min read
DNA lesions are repaired by a cut-and-remove process called nucleotide excision repair. An in vitro biochemically defined system has been developed in which six repair factors are sufficient to excise damage from naked DNA. In the December Molecular and Cellular Biology, Hara et al. use this system to examine the effect of DNA organization into nucleosome structures on the DNA repair process (Mol Cell Biol 2000, 20:9173-9181). A nucleosome structure was assembled by mixing human histone protein
DNA Repair
The Scientist Staff | Jan 5, 1997 | 3 min read
Edited by: Karen Young Kreeger T. Blunt, N.J. Finnie, G.E. Taccioli, G.C.M. Smith, J. Demengeot, T.M. Gottlieb, R. Mizuta, A.J. Varghese, F.W. Alt, P.A. Jeggo, S.P. Jackson, "Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine SCID mutation," Cell, 80:813-23, 1995. (Cited in almost 120 publications as of December 1996) Comments by Frederick W. Alt, Howard Hughes Medical Institute, Children's Hospital, Boston, and Harv
A needle drawing up fluid from an unlabeled vial.
Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
Image showing monoclonal antibody treatment
The Resilience of Monoclonal Antibodies and their Makers
Laura Tran, PhD | Mar 15, 2024 | 10+ min read
The road to developing monoclonal antibodies for effectively targeting cancer was paved with tenacity, passion, and strokes of luck.

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