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With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.

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image: Damage Patroller

Damage Patroller

By | October 1, 2017

Stephen Elledge has built a career studying how eukaryotic cells maintain genomic integrity.

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image: Infographic: The Various Forms of Methylated DNA

Infographic: The Various Forms of Methylated DNA

By | September 1, 2017

To expand the basic nucleotide alphabet, many species modify their DNA with epigenetic marks.

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image: The Role of DNA Base Modifications

The Role of DNA Base Modifications

By | September 1, 2017

Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.

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image: CRISPR: No Cutting Required

CRISPR: No Cutting Required

By | August 4, 2016

Combining a modified Cas9 enzyme with an unrelated one derived from the immune system of the sea lamprey, researchers demonstrate yet another way to edit a single DNA nucleotide. 

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image: Advances in Genome Editing

Advances in Genome Editing

By | April 20, 2016

Researchers develop a CRISPR-based technique that efficiently corrects point mutations without cleaving DNA.

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image: New Way to Edit Genes

New Way to Edit Genes

By | October 1, 2015

Researchers develop a more-efficient method for rewriting DNA that could hold therapeutic value for HIV and other diseases.

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image: Age-Old Questions

Age-Old Questions

By | March 1, 2015

How do we age, and can we slow it down?

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image: How We Age

How We Age

By | March 1, 2015

From DNA damage to cellular miscommunication, aging is a mysterious and multifarious process.

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image: Wrangling Retrotransposons

Wrangling Retrotransposons

By , , and | March 1, 2015

These mobile genetic elements can wreak havoc on the genome. Researchers are now trying to understand how such activity contributes to the aging process.

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