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Researchers use base-editing to swap out an erroneous nucleotide responsible for a potentially life-threatening blood disorder.

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image: A Single Mutation in Zika Led to Devastating Effects

A Single Mutation in Zika Led to Devastating Effects

By | September 28, 2017

One amino acid change within a viral structural protein makes the difference between mild cases of brain damage and severe microcephaly in mice.

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image: Most Accurate CRISPR Gene Editing Yet

Most Accurate CRISPR Gene Editing Yet

By | September 22, 2017

A tweaked Cas9 nuclease reduces off-target effects to levels below that of previous versions of the enzyme.

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image: CRISPR Used in Human Embryos to Probe Gene Function

CRISPR Used in Human Embryos to Probe Gene Function

By | September 20, 2017

OCT4 is necessary for blastocyst formation in the human embryo, researchers report.

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image: Icelanders’ Genomes Hint at Origins of Genetic Diversity

Icelanders’ Genomes Hint at Origins of Genetic Diversity

By | September 20, 2017

An analysis of 14,000 genomes reveals regions where new mutations are more likely to develop.

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image: Cargo-Sorting DNA Robots

Cargo-Sorting DNA Robots

By | September 14, 2017

Autonomous molecules that collect, carry, and sort different genetic packages usher in a new era for nucleic-acid robotics. 

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image: Criticism for Craig Venter’s “Face-Prediction” Software

Criticism for Craig Venter’s “Face-Prediction” Software

By | September 11, 2017

The tool cannot predict a person’s face from DNA, say researchers—including some listed as coauthors on the publication. 

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image: Fingerprints of Ongoing Human Evolution Found

Fingerprints of Ongoing Human Evolution Found

By | September 5, 2017

Genetic variants in Alzheimer’s- and smoking-related genes appear to be under selection pressure, according to a study comparing the genomes of old and young participants.

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Exposure to the body’s humidity causes a film of the microbes to change shape, opening flaps in the garment to allow for increased airflow.

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image: Contributors

Contributors

By | September 1, 2017

Meet some of the people featured in the September 2017 issue of The Scientist.

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