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tag cancer biology culture cell molecular biology

Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Infusion of Artificial Intelligence in Biology
Meenakshi Prabhune, PhD | Feb 23, 2024 | 10 min read
With deep learning methods revolutionizing life sciences, researchers bet on de novo proteins and cell mapping models to deliver customized precision medicines.
TSS
The Art and Science of Synthetic Biology 
The Scientist | Nov 27, 2023 | 2 min read
Researchers get creative using bacterial bits and pieces to produce synthetic cells for studying cancer.
Molecular Biology
The Scientist Staff | Jul 5, 1992 | 1 min read
S.J. Baker, S. Markowitz, E.R. Fearon, J.K.V. Willson, B. Vogelstein, "Suppression of human colorectal carcinoma cell growth by wild- type p53,"Science, 249:912-15, 1990. S.J. Baker, A.C. Preisinger, J.M. Jessup, et al., "p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis," Cancer Research, 50:7717-22, 1990. Bert Vogelstein (Johns Hopkins Oncology Center, Baltimore, Md.): "Cancer represents not one disease but hundreds. Accordingly,
Molecular Biology
The Scientist Staff | Dec 6, 1992 | 2 min read
R. Glynne, S. H. Powis, S. Beck, A. Kelly, L-A. Kerr, J. Trowsdale, "A proteasome-related gene between the two ABC transporter loci in the class II region of the human MHC," Nature, 353:357-360, 1991. Richard Glynne (Imperial Cancer Research Fund, London, England): "The mechanism by which the body's immune system recognizes and kills virally infected cells but passes over healthy cells has intrigued immunologists for many years. An important breakthrough came when Alain Townsend at the John R
Molecular Biology
The Scientist Staff | Dec 9, 1990 | 1 min read
S. Hahn, S. Buratowski, P.A. Sharp, L. Guarente, "Isolation of the gene encoding the yeast TATA binding protein TFIID: a gene identical to the SPT15 suppressor of Ty element insertions," Cell, 58, 1173-81, 22 September 1989. Steven Hahn (Fred Hutchinson Cancer Research Center, Seattle): "TFIID is one of the essential components in the machinery necessary to initiate transcription by RNA polymerase II. For eight years after the discovery of TFIID in mammals, little was known about it because of
Molecular Biology
The Scientist Staff | Nov 22, 1992 | 2 min read
L.-H. Tsai, E. Harlow, M. Meyerson, "Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase," Nature, 353:174-7, 1991. Li-Huei Tsai (Massachusetts General Hospital Cancer Center, Charlestown, Mass.): "Regulation of the onset of cellular DNA synthesis appears to be an important mechanism for small DNA tumor viruses to immortalize cells. Both the retinoblastoma gene product (pRB) and cyclin A, two of the adenovirus E1A targeted cellular proteins, hav
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
MOLECULAR BIOLOGY
The Scientist Staff | Dec 8, 1991 | 2 min read
MOLECULAR BIOLOGY Date: December 9, 1991 D. Anderson, C.A. Koch, L. Grey, C. Ellis, et al., "Binding of SH2 domains of phospholipase Cg1, GAP, and Src to activated growth factor receptors," Science, 250:979-82, 1990. Tony Pawson (Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto): "Many of the hormones that control cell growth, differentiation, and metabolism in the adult, and development in the embryo, bind to the extracellular region of receptors that span th
Molecular Biology-1
The Scientist Staff | Jun 23, 1991 | 1 min read
A.D. Friedman, W.H. Landschulz, S.L. McKnight, "CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells," Genes & Development, 3: 1314-22, 1989. Alan D. Friedman (Johns Hopkins Oncology Center, Baltimore): "CCAAT/enhancer binding protein (C/EBP) is perhaps best known as the prototypical basic region-leucine zipper DNA-binding protein (Science, 243:1681-88, 1989). This paper, however, represents part of the earliest efforts of the McKnight labo

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