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image: Infographic: Piecing the Cholesterol Puzzle

Infographic: Piecing the Cholesterol Puzzle

By Diana Kwon | May 1, 2018

How a rare disease led to an understanding of the basics of cholesterol regulation.

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image: Infographic: Rare Disease by the Numbers

Infographic: Rare Disease by the Numbers

By The Scientist Staff | May 1, 2018

How rare conditions and research spending on them compare with more common diseases.

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image: Slow March Toward a Canavan Cure

Slow March Toward a Canavan Cure

By Ashley Yeager | May 1, 2018

Two decades after a successful crowdfunding campaign, some clinical trial patients have seen improvements—but there’s still no approved treatment for the disease.

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Though Calliope Joy’s disease is too far progressed to be treatable, her parents have helped other children with metachromatic leukodystrophy get access to an experimental therapy.

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DNA from a relative of the suspect submitted to the site GEDmatch gave investigators just enough information to identify him, but the process raises privacy concerns.

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A trio of papers provide new insight into embryo development.

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image: Preterm Labor May Be Sparked by Fetal Immune Reaction

Preterm Labor May Be Sparked by Fetal Immune Reaction

By Ruth Williams | April 25, 2018

Immune cells targeting maternal antigens are abundant in the blood of premature infants, suggesting fetal intolerance of mom may instigate early labor.  

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Researchers used the genome sequence of Artemisia annua to boost the plant’s production of artemisinin.

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image: Image of the Day: Immune Cell In Action

Image of the Day: Immune Cell In Action

By The Scientist Staff | April 23, 2018

By combining two new microscopy technologies, researchers filmed immune cells toiling away in the inner ear of a living zebrafish.

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image: Free Divers From Southeast Asia Evolved Bigger Spleens

Free Divers From Southeast Asia Evolved Bigger Spleens

By Anna Azvolinsky | April 19, 2018

The adaptation gives better endurance to the Bajau people, known as sea nomads, by increasing spleen size and, in turn, boosting the number of oxygenated red blood cells when diving.  

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