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tag rare diseases disease medicine developmental biology immunology

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Cropped view of senior man playing with puzzles
A Rare Genetic Mutation Protects Against Alzheimer's Disease
Hannah Thomasy, PhD, Drug Discovery News | Sep 17, 2023 | 4 min read
Data from a highly resilient individual guided researchers to new potential therapeutic targets.
The Challenges of Rare-Disease Research
Jyoti Madhusoodanan | Sep 1, 2016 | 8 min read
With few resources and hesitant investors, basic scientists must rely on clinicians, patient advocates, and their own keen eye for biological connections.
New Strategies to Discover Human Disease Genes
New Strategies to Discover Human Disease Genes
The Scientist | Oct 16, 2023 | 2 min read
Learn how researchers across health-related fields identify and characterize disease-causing genomic variants.
3D illustration of damaged myelin sheath seen in demyelinating diseases such as multiple sclerosis.
Tracking Down Innate Immune Cells in Multiple Sclerosis
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 5 min read
A novel PET tracer targeting a receptor in myeloid cells can help monitor disease progression in a mouse model of multiple sclerosis.
An illustration of a pregnant women wearing a mask, surrounded by microbes
How COVID-19 Affects Pregnancy
Amanda Heidt | Aug 16, 2022 | 10 min read
Evidence thus far shows that pregnant people infected with SARS-CoV-2 are at higher risk for severe disease and death, as well as complications in their pregnancies.
A three-dimensional rendered image of neuron cell network on black background.
Assembloids Unlock the Roles of Key Neurodevelopment Disease Genes
Aparna Nathan, PhD | Sep 27, 2023 | 3 min read
Brain-like tissue grown in a dish mimics critical periods for development and reveals how it can go wrong.
Journal club logo on purple background
The Scientist's Journal Club: Transcriptomics
The Scientist | Sep 20, 2023 | 2 min read
Scientists discuss their latest findings on immune cell dynamics, neurodegenerative disease risk factors, and rare cell types obtained from bulk and single cell RNA sequencing experiments.
neuron surrounded by immune cells
Meningitis Bacteria Trigger Headaches, Then Sneak Into the Brain
Natalia Mesa, PhD | Mar 6, 2023 | 3 min read
Researchers find that bacteria stimulate a headache-causing pain pathway to suppress the immune system and infect the brain. 
Valerie Arboleda Uses Big Data to Unravel the Biology of a Rare Disease
Shawna Williams | May 1, 2018 | 3 min read
The UCLA geneticist examines how defects in a histone protein lead to symptoms throughout the body.

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