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tag rare diseases evolution cell molecular biology microbiology
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD
| Mar 14, 2024
| 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.
A Journey Into the Brain
Danielle Gerhard, PhD
| Mar 22, 2024
| 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Are Phages Overlooked Mediators of Health and Disease?
Catherine Offord
| Feb 1, 2021
| 10+ min read
Bacteria-infecting viruses affect the composition and behavior of microbes in the mammalian gut—and perhaps influence human biology.
Deficient RNA Editing Implicated in Inflammatory Disease
Alejandra Manjarrez, PhD
| Aug 5, 2022
| 3 min read
Genetic variants that reduce the editing levels of double-stranded RNA are associated with autoimmune and immune-mediated conditions, a study finds.
Fungal Spores Hijack a Host Protein to Escape Death
Mariella Bodemeier Loayza Careaga, PhD
| Jun 20, 2023
| 3 min read
Uncovering the components used by
Aspergillus fumigatus
to avoid intracellular destruction broadens our understanding of the mold’s pathogenesis.
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord
| Jul 1, 2021
| 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
How Bacterial Communities Divvy up Duties
Holly Barker, PhD
| Jun 1, 2023
| 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
Cooperation and Cheating
Mariella Bodemeier Loayza Careaga, PhD
| Jun 1, 2023
| 6 min read
Bacteria cooperate to benefit the collective, but cheaters can rig the system. How is the balance maintained?
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