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image: Ruth Nussenzweig, Malaria Researcher, Dies

Ruth Nussenzweig, Malaria Researcher, Dies

By Jim Daley | April 6, 2018

The microbiologist’s research led to the development of the first human malaria vaccine.

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image: A Neuroscientist’s Journey Through Madness

A Neuroscientist’s Journey Through Madness

By Barbara Lipska with Elaine McArdle | April 1, 2018

After I was diagnosed with brain cancer and started to lose my mental health, the importance of my job came into clear focus.

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Mice treated with an immunostimulant had better outcomes when researchers blocked the expression of TNFR2, a compound that helps tumors evade immune attack.

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In the presence of cytosolic DNA, cancer cells activate antiviral pathways that disguise them as immune cells.

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With three recent FDA approvals, and a number of Phase 3 trials ongoing, the drugs are seeing a surge in interest.

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Errors in segregation during cell division can lead to inflammation in daughter cells.

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The drugs’ disruption of the microbiome makes a subsequent flavivirus infection more severe.

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A study finds that the vaccine’s effects wear off as a person ages, suggesting a need for booster shots.

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The agency gave personal genomics company 23andMe the green light to screen samples for breast cancer–related genetic mutations.

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In response to short DNA fragments, lymphocytes release mitochondrial DNA that helps trigger an immune response.

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