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tag brca1 disease medicine developmental biology microbiology evolution

Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Contributors
Abby Olena, PhD | Mar 1, 2014 | 3 min read
Meet some of the people featured in the March 2014 issue of The Scientist.
Notebook
Eugene Russo | Dec 5, 1999 | 7 min read
Contents Pivotal pump Leptin limbo Clue to obesity Biotech Web site Helping hand Mapping malaria Notebook Pictured above are pigmented bacterial colonies of Deinococcus radiodurans, the most radiation-resistant organism currently known. DEINO-MITE CLEANUP In 1956, investigators discovered a potentially invaluable cleanup tool in an unlikely place. A hardy bacterium called Deinococcus radiodurans unexpectedly thrived in samples of canned meat thought to be sterilized by gamma radiation. The b
NAS Honors 15 For Contributions To Science
Eugene Russo | Apr 26, 1998 | 7 min read
Seven life scientists are among the 15 honorees for this year's National Academy of Sciences award ceremony set for today at the NAS's 135th annual meeting in Washington, D.C. The meeting also includes the induction of academy members elected last year (E.R. Silverman, The Scientist, 11[9]:1, April 28, 1997). The academy is presenting its highest honor, the Public Welfare Medal, to David A. Hamburg, president emeritus of the Carnegie Corp. of New York. Hamburg, 72, is being recognized "for his
A Push and a Pull for PARP-1 in Aging
Jack Lucentini(jlucentini@the-scientist.com) | Aug 1, 2005 | 6 min read
Understanding the mechanisms that underlie aging remains a bedeviling problem, but not because of a lack of answers.
MMTV and Breast Cancer
Douglas Steinberg | Apr 16, 2000 | 7 min read
Virus-Disease Links Are Hard to Forge Researchers confront skepticism, conflicting results, limited funding By Douglas Steinberg If genomics is glitzy nowadays, virus research is, well, gritty. Its latest heyday, when HIV was shown to cause AIDS, only masked its true nature. Associating viruses with diseases has always been particularly difficult and labor intensive. Cause-and-effect relationships are maddeningly elusive.1 Consider the following two questions: Does infection by mouse mammary
Comparative Genomics Reveals The Interrelatedness Of Life
Ricki Lewis | Jan 4, 1998 | 7 min read
Photo: Karen Young Kreeger EXCITING ERA: TIGR's Craig Venter says efforts to unravel the information being gathered will last "into the next century." While the list of genome projects grows, research focus is shifting from structure to function. So even as automated DNA sequencers crank out bases and powerful software overlaps pieces of genomes (contigs) to establish gene orders, investigators are searching and comparing those sequences among species, an approach called comparative genomics.
Working in a Virtual Laboratory
Jennifer Fisher Wilson | Dec 6, 1998 | 6 min read
NEXT STEP: The virtual center "is the natural evolution of our shared research interests," says Ashley T. Haase, chair of the microbiology department at the University of Minnesota. When AIDS researchers physically located in four different states hold a meeting, it almost feels like they're sitting at a table across from each other--but they're really just facing their individual computer screens. They view slides of the human immunodeficiency virus in lymphoid tissue in real time and discuss

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