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tag brca1 genetics genomics disease medicine
The Largest Whole-genome Sequencing Study in Cancer
Danielle Gerhard, PhD
| Apr 17, 2024
| 7 min read
Comprehensive genome sequencing of 13,880 tumors revealed somatic and germline mutations that could influence patient treatment and prognosis.
An Epigenetic Strategy to Control Bad Cholesterol
Maggie Chen
| Apr 12, 2024
| 3 min read
Modifying markers on DNA allows scientists to lower cholesterol levels in mice, even long-term.
Cell Surface RNA Helps Neutrophils Get Around
Holly Barker, PhD
| Apr 2, 2024
| 4 min read
A new study confirms reports of membrane-bound RNA molecules and points to their role in neutrophil migration.
Biological Sex Influences Brain Protein Expression
Shelby Bradford, PhD
| Apr 4, 2024
| 3 min read
Neurological disorders often have sex biases, and these differences could be due to altered protein expression in the brain.
Stem Cell Editing Repairs Severe Immunodeficiency
Kamal Nahas, PhD
| Mar 20, 2024
| 5 min read
Scientists hoping to treat immunodeficiencies using gene therapy have found a way to edit stem cells in mice without disrupting gene regulation.
A Journey Into the Brain
Danielle Gerhard, PhD
| Mar 22, 2024
| 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
Turning on the Bat Signal
Hannah Thomasy, PhD
| Mar 15, 2024
| 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Tapping into Immunotherapy’s Potential to Help More People
The Scientist
Staff
| Mar 8, 2024
| 2 min read
Discover what researchers have learned about varying immunotherapy response rates between patients with the same cancer types.
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