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tag fetal brain neuroscience disease medicine

Exploring the Past, Present, and Future of Brain Organoids 
Niki Spahich, PhD | Feb 18, 2024 | 5 min read
Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
Neuroscience/ Alzheimer's Disease Research
Karen Young Kreeger | Feb 18, 1996 | 2 min read
Comments by Virginia M.-Y. Lee and John Q. Trojanowski, University of Pennsylvania School of Medicine New Twist On Tangles: Research conducted by Penn's John Trojanowski and Virginia Lee suggests that phosphatases may be "lazy," or inactive, in Alzheimer's tangles. This paper offers a new way of looking at the formation of tangles-a twisted neuronal knot of paired helical filaments (PHFs). PHFs are one of the two primary diagnostic features found in the brains of Alzheimer's disease (AD) pat
3D image of a neuron cell network with a red glow representing inflammation.
New Insight into Brain Inflammation Inspires New Hope for Epilepsy Treatment 
Deanna MacNeil, PhD | Jun 1, 2023 | 2 min read
Clinicians and researchers teamed up to investigate how inappropriate proinflammatory mechanisms contribute to the pathogenesis of drug-refractory epilepsy.
Brain cell in purple on a black background. Arc mRNAs are labeled green and are mainly localized in the cell nucleus and in the dendrites.
Short-lived Molecules Support Long-term Memory 
Alejandra Manjarrez, PhD | Jun 6, 2023 | 3 min read
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.
Thousands of Mutations Accumulate in the Human Brain Over a Lifetime
Ruth Williams | Dec 7, 2017 | 4 min read
Single-cell genome analyses reveal the amount of mutations a human brain cell will collect from its fetal beginnings until death.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Stem Cell Transplant Treats Parkinson’s Disease in Monkeys
Roni Dengler, PhD | Feb 7, 2022 | 4 min read
Personalized stem cells improved motor symptoms and depression signs in monkeys modeling Parkinson’s disease, paving the way for trials in human patients.
Neuroscience: A Personal Perspective
Paul Smaglik | Sep 12, 1999 | 4 min read
When Paul R. Sanberg became a neuroscientist, he focused on Huntington's disease. When he realized that Parkinson's disease was related, he expanded his horizons. And when his father suffered a stroke about five years ago, he shifted his priorities. Some of the things he has learned since may help treat all three diseases, as well as a number of other neurodegenerative disorders. Following his father's stroke, Sanberg recalls months of trips between Tampa, where he worked as a researcher for t
Mapping Brain Proteins
Devika G. Bansal | Feb 1, 2018 | 7 min read
Researchers are using souped-up mass spectrometry to localize proteins within brain cells.

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