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tag prefrontal cortex disease medicine

early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021 | 5 min read
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Amyloid plaques (stained for amyloid-? peptide) detected in a post-mortem brain sample of a patient with Alzheimer's disease. Purple purple dots in the background are the nuclei of neurons and glia.
Herpes Viruses Implicated in Alzheimer’s Disease
Anna Azvolinsky | Jun 21, 2018 | 5 min read

A new study shows that the brains of Alzheimer’s disease patients have a greater viral load, while another study in mice shows infection leads to amyloid-β build up.

Researchers Pry into Schizophrenia's Stubborn Secrets
Steve Bunk | Sep 12, 1999 | 7 min read
Adapted from image courtesy of Lynn D. Selemon Stereologic cell counting of prefrontal cortical area 9. Nissl-stained neurons (shown as triangles and dots) were counted directly in a stack of three-dimensional boxes extending throughout all layers of the cortex. Could any major illness be more difficult to study than schizophrenia? Despite unprecedented advances in research over recent years, largely aided by improved neuroimaging technologies, little is known for sure about either its origins
Cartoon of a silhouetted person’s bright pink brain being shocked by jumper cables
Electrically Zapping Specific Brain Regions Can Boost Memory
Dan Robitzski | Aug 22, 2022 | 3 min read
Low-intensity electrical stimulation allows older adults to better recall a list of words for at least a month following the treatment, a study finds, providing further evidence for the debated idea that electrical stimulation can enhance cognitive performance.
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
Illustration of gray bacteriophages approaching and infecting a red and orange bacteria that has multiple fimbria protruding from it.
Bacteria-Infecting Viruses in Gut Microbiome Linked to Cognition
Dan Robitzski | Feb 16, 2022 | 5 min read
Research in mice and flies suggests that bacteriophages, including those found in dairy foods, may have an influence on an animals’ ability to learn and remember information.
Conceptual image of numbers
Is Your Brain Wired for Numbers?
Catherine Offord | Oct 1, 2021 | 10+ min read
Our perception of quantity, separate from counting or estimation of magnitude more generally, is foundational to human cognition, according to some neuroscientists.
How Manipulating Rodent Memories Can Elucidate Neurological Function
Amber Dance | May 1, 2020 | 10+ min read
Strategies to make lab animals forget, remember, or experience false recollections probe how memory works, and may inspire treatments for neurological diseases.
Broken Heart Syndrome Linked to the Brain
Amanda Heidt | Jun 1, 2021 | 2 min read
A chronically stressed amygdala can prime the heart to overreact to acute stress events, a new study shows.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.

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