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Three Autism-Linked Genes Converge on Tweaks to Cells’ Timing
Three Autism-Linked Genes Converge on Tweaks to Cells’ Timing
The genes are involved in pacing the development of inhibitory and excitatory neurons. An imbalance in these two types of signaling is thought to play a role in autism.
The genes are involved in pacing the development of inhibitory and excitatory neurons. An imbalance in these two types of signaling is thought to play a role in autism.
mutations, neuroscience
Combinatorial Single Cell CRISPR Screens: Challenges and Applications
The Scientist Creative Services Team in collaboration with 10x Genomics | Dec 10, 2021 | 2 min read
An expert panel will discuss how single cell sequencing enhances throughput in CRISPR gene editing applications.
Genes for Alcohol Use Disorder and Alzheimer’s Risk Overlap: Study
Emma Yasinski | Aug 24, 2021 | 4 min read
Genetic, transcriptomic, and epigenetic data reveal molecular mechanisms tying these disorders to each other and to immune disfunction.
Participant’s Diagnosis Halts Gene Therapy Clinical Trial
Amanda Heidt | Aug 12, 2021 | 3 min read
The FDA pauses the research program on a lentivirus-based treatment for a rare neurological condition after a patient developed a bone marrow disorder that could presage leukemia.
Thousands of Mutations Accumulate in the Human Brain Over a Lifetime
Ruth Williams | Dec 7, 2017 | 4 min read
Single-cell genome analyses reveal the amount of mutations a human brain cell will collect from its fetal beginnings until death.
More Mutations in Girls with Autism
Kerry Grens | Mar 4, 2014 | 1 min read
A greater number of genetic mutations among autistic girls, compared to their male counterparts, suggests that the female brain can better handle such variations.
Fast Worms
Kerry Grens | Jan 1, 2013 | 2 min read
A microfluidic device scans individual C. elegans for abnormal traits and sorts wild-type animals from mutants.
Fewer Mutations in Tumor Mitochondria
Hayley Dunning | Jun 7, 2012 | 3 min read
Contrary to existing dogma, colon cancer cell mitochondria carry fewer mutations than mitochondria of normal body cells.
Deconstructing the Mosaic Brain
Tom Curran | Aug 1, 2011 | 5 min read
Sequencing the DNA of individual neurons is a way to dissect the genes underlying major neurological and psychological disorders.