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image: Opinion: We Have Been Naive About Naive T Cells

Opinion: We Have Been Naive About Naive T Cells

By Theo van den Broek, José A.M. Borghans, and Femke van Wijk | April 6, 2018

Human naive T cells are far more heterogeneous than has long been appreciated, having implications for vaccine strategies.

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image: Ruth Nussenzweig, Malaria Researcher, Dies

Ruth Nussenzweig, Malaria Researcher, Dies

By Jim Daley | April 6, 2018

The microbiologist’s research led to the development of the first human malaria vaccine.

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Mice treated with an immunostimulant had better outcomes when researchers blocked the expression of TNFR2, a compound that helps tumors evade immune attack.

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In the presence of cytosolic DNA, cancer cells activate antiviral pathways that disguise them as immune cells.

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Errors in segregation during cell division can lead to inflammation in daughter cells.

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Last year, researchers claimed the gene-editing method had accuracy issues, but a new whole-genome sequencing analysis by the same team finds otherwise.

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The drugs’ disruption of the microbiome makes a subsequent flavivirus infection more severe.

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A study finds that the vaccine’s effects wear off as a person ages, suggesting a need for booster shots.

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image: Monitoring Mutations with Microfluidics

Monitoring Mutations with Microfluidics

By Ruth Williams | March 15, 2018

A device dubbed the “mother machine” enables real-time observation of mutagenesis in single bacterial cells.  

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The agency gave personal genomics company 23andMe the green light to screen samples for breast cancer–related genetic mutations.

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