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image: Infographic: Breaking into the Brain

Infographic: Breaking into the Brain

By Amanda B. Keener | November 1, 2017

The blood-brain barrier is a collection of specialized cells and proteins that control the movement of molecules from the blood to the central nervous system.

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image: Getting Drugs Past the Blood-Brain Barrier

Getting Drugs Past the Blood-Brain Barrier

By Amanda B. Keener | November 1, 2017

To treat neurological disease, researchers develop techniques to bypass or trick the guardian of the central nervous system.

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Research in human patients and mice reveals the role of the circadian clock in the risk of heart damage at different times of day.

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With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.

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image: CRISPR System Targets RNA in Mammalian Cells

CRISPR System Targets RNA in Mammalian Cells

By Anna Azvolinsky | October 4, 2017

Researchers engineer bacterial CRISPR-Cas13 to knock down RNA in mammalian cells.

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image: Image of the Day: Fragile Brain

Image of the Day: Fragile Brain

By The Scientist Staff | October 3, 2017

In Fragile X syndrome—a genetic mishap that results in cognitive delays—the lack of a translation-repressing protein leads to the rampant accumulation of other proteins in the mouse brain.

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image: Damage Patroller

Damage Patroller

By Anna Azvolinsky | October 1, 2017

Stephen Elledge has built a career studying how eukaryotic cells maintain genomic integrity.

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The 38-year-old synthetic biologist comes from a long line of tinkerers and engineers.

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image: Live Cell Extractions

Live Cell Extractions

By Ruth Williams | October 1, 2017

Nanostraws that collect specimens from cells without killing them allow for repeated sampling.

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image: Microglia Turnover in the Human Brain

Microglia Turnover in the Human Brain

By Shawna Williams | October 1, 2017

Researchers find that about a quarter of the immune cells are replaced every year.

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