The Scientist

» RNAi

Most Recent

image: CRISPR System Targets RNA in Mammalian Cells

CRISPR System Targets RNA in Mammalian Cells

By Anna Azvolinsky | October 4, 2017

Researchers engineer bacterial CRISPR-Cas13 to knock down RNA in mammalian cells.


Two freely available databases include data on hundreds of human cancer cell lines. 

1 Comment

image: Mammalian Immunity: What’s RNAi Got to Do with It?

Mammalian Immunity: What’s RNAi Got to Do with It?

By Shawna Williams | July 21, 2017

A new study adds to the evidence that mammalian cells can use small interfering RNAs to defend against viruses, but questions remain about physiological importance.

1 Comment

image: First RNAi Insecticide Approved

First RNAi Insecticide Approved

By Aggie Mika | June 27, 2017

This month, the EPA registered four products that include RNA interference technology intended to control corn rootworms. 


image: The RNA Age: A Primer

The RNA Age: A Primer

By Ruth Williams | May 11, 2017

Our guide to all known forms of RNA, from cis-NAT to vault RNA and everything in between.


image: RNAi’s Future in Drug-Target Screening

RNAi’s Future in Drug-Target Screening

By Catherine Offord | April 17, 2017

A recent CRISPR study contradicted years of RNA interference research on a well-studied cancer drug target. But is it the last nail in the coffin for RNAi as a screening tool? 


image: RNA Interference Between Kingdoms

RNA Interference Between Kingdoms

By Kerry Grens | February 1, 2017

Plants and fungi can use conserved RNA interference machinery to regulate each other’s gene expression—and scientists think they can make use of this phenomenon to create a new generation of pesticides.


image: Oligonucleotide Therapeutics Near Approval

Oligonucleotide Therapeutics Near Approval

By Catherine Offord | December 1, 2016

Successful late-stage clinical trials could mark the maturation of a new drug development platform, but the path to commercialization is not without hurdles.


image: Gut Bacteria Vectors

Gut Bacteria Vectors

By Ruth Williams | June 1, 2016

Researchers mix bacteria genetically engineered to express double-stranded RNA into insect food.


image: Questions Over <em>C. elegans</em> Life Span Factors

Questions Over C. elegans Life Span Factors

By Catherine Offord | June 1, 2016

A recent paper challenges earlier findings that germline factors expressed in normal body cells influence life span in C. elegans.


Popular Now

  1. Could Rapamycin Help Humans Live Longer?
  2. Renowned Physicist Stephen Hawking Dies
  3. John Sulston, Human Genome Project Leader, Dies
  4. Pupil Response to an Optical Illusion Tied to Autistic Traits