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image: The Second Coming of RNAi

The Second Coming of RNAi

By | September 1, 2014

Now showing clinical progress against liver diseases, the gene-silencing technique begins to fulfill some of its promises.

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image: Roche Set to Buy RNAi Firm

Roche Set to Buy RNAi Firm

By | August 6, 2014

The Swiss pharmaceutical giant will reportedly pay $450 million for a Danish biotech company that develops drugs that silence microRNAs.

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image: Unraveling the Female Fruit Fly Mating Circuit

Unraveling the Female Fruit Fly Mating Circuit

By | July 2, 2014

Three teams identify different components of the female Drosophila nervous system that govern mating behaviors.

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image: Exploring the Roles of Enhancer RNAs

Exploring the Roles of Enhancer RNAs

By | May 7, 2014

Scientists have recently discovered that enhancers are often transcribed into RNAs. But they’re still not sure what, if anything, these eRNAs do.

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image: Fighting Viruses with RNAi

Fighting Viruses with RNAi

By | October 10, 2013

The long-debated issue of whether mammals can use RNA interference as an antiviral defense mechanism is finally put to rest.

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image: RNAi Remedy Lowers Cholesterol

RNAi Remedy Lowers Cholesterol

By | October 3, 2013

A Phase 1 clinical trial demonstrates the safety and efficacy of an siRNA-based, cholesterol-lowering drug.

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image: Gene Silencing Is Golden

Gene Silencing Is Golden

By | August 1, 2013

A beginner’s how-to on RNAi screening in mammalian cells

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image: Shushing RNA

Shushing RNA

By | August 1, 2013

The cell detains potentially harmful RNA messages in the spliceosome long enough to create interfering RNAs against the aberrant messages.

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image: Why Women’s Eggs Don’t Last

Why Women’s Eggs Don’t Last

By | February 13, 2013

As reproductive tissues age, DNA repair mechanisms become less efficient, causing genomic damage to accumulate.

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image: Going Boldly Forth

Going Boldly Forth

By | January 1, 2013

Gregory Hannon believes in taking risks—an approach that’s enabled him to make exciting new discoveries in the world of small RNAs.

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