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image: Infographic: Breaking into the Brain

Infographic: Breaking into the Brain

By | November 1, 2017

The blood-brain barrier is a collection of specialized cells and proteins that control the movement of molecules from the blood to the central nervous system.

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image: Getting Drugs Past the Blood-Brain Barrier

Getting Drugs Past the Blood-Brain Barrier

By | November 1, 2017

To treat neurological disease, researchers develop techniques to bypass or trick the guardian of the central nervous system.

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Research in human patients and mice reveals the role of the circadian clock in the risk of heart damage at different times of day.

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With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.

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image: Opinion: Share Your Data

Opinion: Share Your Data

By , , and | October 24, 2017

Our analysis of a collection of open-access datasets quantifies their benefit to the scientific community.

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image: FDA Approves Second CAR T-Cell Therapy

FDA Approves Second CAR T-Cell Therapy

By | October 19, 2017

The therapy, produced by Kite Pharma and owned by Gilead Sciences, is approved for use against some types of large B-cell lymphomas. 

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These researchers join around 200 research institutions that have cut ties with the publishing giant to support the ongoing push for open access and favorable pricing.

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image: Compound Found in Red Wine Boosts Immune Cell Function

Compound Found in Red Wine Boosts Immune Cell Function

By | October 17, 2017

At low doses, resveratrol enhanced human T-cell activity in vitro, while at high doses it interfered with cell signaling. 

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image: Cancers Relapse by Feeding Off Immune Signals

Cancers Relapse by Feeding Off Immune Signals

By | October 16, 2017

In mice, the tumor cells are able to thwart the immune response that would kill them—but immunotherapy prevented the return of melanoma.

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image: Papers Based on Misidentified Cell Lines Top 32,000

Papers Based on Misidentified Cell Lines Top 32,000

By | October 16, 2017

An analysis of contaminated literature finds that tens of thousands of papers used cell lines of questionable origins—and these were in turn cited by hundreds of thousands of other papers.

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