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Spark Therapeutics’s Luxturna would be the first approved therapy in the U.S. that replaces or repairs a defective gene inherited from one’s parents.

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Combined transcription and genome data from multiple tissues in hundreds of human donors reveal links between genotype and gene expression across the body.

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image: Image of the Day: Overkill

Image of the Day: Overkill

By | October 6, 2017

The Sakishima habu (pitviper; Protobothrops elegans) can compensate for inept traits in the chemical composition of its venom by overdosing its prey.

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Tissue recipients were treated as “guinea pigs,” says investigation leader.

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Mice receiving the treatment produced their own monoclonal antibodies and survived infection with the life-threatening pathogen Pseudomonas aeruginosa.

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image: Image of the Day: Fragile Brain

Image of the Day: Fragile Brain

By | October 3, 2017

In Fragile X syndrome—a genetic mishap that results in cognitive delays—the lack of a translation-repressing protein leads to the rampant accumulation of other proteins in the mouse brain.

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image: Giants of Circadian Biology Win Nobel Prize

Giants of Circadian Biology Win Nobel Prize

By | October 2, 2017

The award in Physiology or Medicine goes to chronobiologists Jeffrey Hall, Michael Rosbash, and Michael Young.

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image: Bathtub Bloodbath, 1793

Bathtub Bloodbath, 1793

By | October 1, 2017

French revolutionary Jean-Paul Marat took on many roles over the course of his life, including physician and scientist.

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Researchers suggest that the receptors can control early labor contractions.

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image: Contributors

Contributors

By | October 1, 2017

Meet some of the people featured in the October 2017 issue of The Scientist.

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