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image: Researchers Make Knockout Stem Cell Lines in One Step

Researchers Make Knockout Stem Cell Lines in One Step

By | December 1, 2017

Combining gene editing and stem-cell induction improves efficiency of functional genetic analyses.

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image: Infographic: Combo Method of Stem Cell Generation

Infographic: Combo Method of Stem Cell Generation

By | December 1, 2017

Simultaneous exposure to reprogramming and gene-editing plasmids efficiently produces edited pluripotent colonies.

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Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.

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Neurons derived from human induced pluripotent stem cells fill in for lost dopamine neurons in a primate model of the disease.

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image: Opinion: Biobanking Has a Consent Dilemma

Opinion: Biobanking Has a Consent Dilemma

By | July 25, 2017

Is the deep uncertainty surrounding fundamental legal and ethical norms putting biobanks in a precarious position? 

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image: Women Lose Vision After Stem Cell Treatment

Women Lose Vision After Stem Cell Treatment

By | March 17, 2017

The adipose-derived cells were injected into the patients’ eyes to treat age-related macular degeneration. 

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image: Suicide Switch for Transplanted Stem Cells

Suicide Switch for Transplanted Stem Cells

By | March 2, 2017

Researchers use an inducible gene to limit tumor growth from human iPSCs transplanted into mice.

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image: Regulators OK Clinical Trials Using Donor Stem Cells

Regulators OK Clinical Trials Using Donor Stem Cells

By | February 6, 2017

Japanese health officials approve human experiments to treat macular degeneration with a cell therapy derived from induced pluripotent stem cells.

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image: Induced Pluripotent Stem Cells Show Signs of Donor Age

Induced Pluripotent Stem Cells Show Signs of Donor Age

By | December 12, 2016

iPSCs created through the reprogramming of human somatic cells retain genomic marks of the donor’s age.

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While studying a rare genetic disease, researchers discovered a signaling pathway linked to the efficiency of reprogramming somatic cells into stem cells.

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