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Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.

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By converting glial cells into dopaminergic neurons, scientists were able to partially rescue motor behavior in mice.

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image: Stem Cells Made Waves in Biology and Medicine

Stem Cells Made Waves in Biology and Medicine

By | October 1, 2016

Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.

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image: Study: Mitotic Cells Can Reprogram Mouse Sperm

Study: Mitotic Cells Can Reprogram Mouse Sperm

By | September 13, 2016

Murine embryos undergoing first cell division can reprogram injected sperm and develop normally. 

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Researchers use the CRISPR/Cas system to express three transcription-factor genes, changing the identities of mouse cells.

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image: Programming Pancreatic Cells

Programming Pancreatic Cells

By | January 7, 2016

Researchers reprogram human skin cells to make insulin-producing pancreatic cells that can prevent diabetes in mice.

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image: Pluripotency Bots

Pluripotency Bots

By | January 1, 2016

A tour of efforts to automate the production and differentiation of induced pluripotent stem cells

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image: Stem Cell Similarities

Stem Cell Similarities

By | October 28, 2015

Human induced pluripotent stem cells appear functionally equivalent to stem cells from embryos in a study.

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image: Neurons from Glia In Vivo

Neurons from Glia In Vivo

By | October 19, 2015

Scientists present new recipes for directly converting glial cells to neurons in mouse brains.

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image: Chemical Cocktails Produce Neurons

Chemical Cocktails Produce Neurons

By | August 6, 2015

Two research groups have devised small-molecule recipes to directly transform fibroblasts into neurons.

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