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» DNA methylation and developmental biology

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Skeleton Keys

By Lewis Wolpert | May 14, 2011

There are a surprising number of unknowns about how our limbs come to be symmetrical.

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image: Taking Shape

Taking Shape

By Richard P. Grant | April 1, 2011

Floral bouquets are the most ephemeral of presents. The puzzle of how flowers get their shape, however, is more enduring. 

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image: The Footprints of Winter

The Footprints of Winter

By Ralf Müller and Justin Goodrich | March 1, 2011

Epigenetic marks laid down during the cold months of the year allow flowering in spring and summer.

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image: Epigenetic Changes in Cancer

Epigenetic Changes in Cancer

By Manel Esteller | March 1, 2011

The study of how covalent marks on DNA and histones are involved in the origin and spread of cancer cells is also leading to new therapeutic strategies.

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The Mark of Faith

By Robert E. Kingston | March 1, 2011

Testing a central tenet of epigenetic regulation

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image: Epigenetics and Society

Epigenetics and Society

By Andrew D. Ellington | March 1, 2011

Did Erasmus Darwin foreshadow the tweaking of his grandson’s paradigm?

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Ready, Reset, Go

By Karen Hopkin | March 1, 2011

Rudolf Jaenisch enjoys climbing mountains, rafting rapids, and unraveling the secrets of pluripotency—knowledge that could someday lead to personalized regenerative medicine.

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image: Epigenetics—A Primer

Epigenetics—A Primer

By Stefan Kubicek | March 1, 2011

There are many ways that epigenetic effects regulate the activation or repression of genes. Here are a few molecular tricks cells use to read off the right genetic program.

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image: Epigenetics—A Primer

Epigenetics—A Primer

By Stefan Kubicek | March 1, 2011

Epigenetic events regulate the activities of genes without changing the DNA sequence. Different genes are expressed depending on the methyl-marks attached to DNA itself and by changes in the structure and/or composition of chromatin. 

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image: Environmental Impact

Environmental Impact

By David Berreby | March 1, 2011

Research in behavioral epigenetics is seeking evidence that links experience to biochemistry to gene expression and back out again.

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