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tag digital pcr developmental biology disease medicine culture

Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
Valerie Arboleda Uses Big Data to Unravel the Biology of a Rare Disease
Shawna Williams | May 1, 2018 | 3 min read
The UCLA geneticist examines how defects in a histone protein lead to symptoms throughout the body.
Defining Rare Disorders: A Profile of Judith Hall
Anna Azvolinsky | Sep 1, 2019 | 8 min read
By bringing genetics into clinical medicine, the University of British Columbia medical geneticist helped to identify the gene mutations responsible for many rare diseases.
The Spin on Rotary Culture
A. J. S. Rayl | Oct 27, 2002 | 9 min read
Image: Courtesy of Leoncio A. Vergara, UTMB, Marguerite Sognier & Nasa/JSC Musculoskeletal Tissue Engineering Lab SPACE-AGE CELL CULTURE: This 3-D human rhabdomyosarcoma cell aggregate was grown in a disposable High Aspect-Ratio Vessel (HARV) in Synthecon's Rotating Cell Culture System. Biotechnology advances at a furious pace, yet for the most part, cell culture remains fixed in the past. Over the last decade, however, a new technology has emerged that models the microgravity of space--
Going Their Separate Ways: A Profile of Products for Cell Separation
Michelle Vettese-dadey | Sep 12, 1999 | 10+ min read
Date: September 13, 1999Cell Separation Products Magnetic Cell Separation Technologies that isolate rare cell types to high purity are essential to the cell biology researcher. Understanding cell developmental pathways becomes increasingly significant as diagnosis and treatment of disease turns more to the molecular level.1 This diagnosis of cell-related diseases requires methods for detection, isolation, and analysis of individual cells regardless of their frequency.2 The hematopoietic system
PCR Primed To Spur Chain Of Applications
Holly Ahern | Jun 25, 1995 | 10+ min read
What would you do if your research interests revolved around obtaining DNA from a bacterium preserved for millions of years in the gut of a bee stuck in amber, matching up a murderer to crime- scene blood half a century old, or cloning genes from a 1,000- year-old mummy? Most scientists would first consider PCR--the polymerase chain reaction--as a technique for approaching problems such as these. With PCR, minute quantities of nucleic acids can be amplified millions of times into sufficient qua
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
'Limitless' PCR Technology Offers Scientists Vast Variety Of Applications
Holly Ahern | Feb 4, 1996 | 10 min read
With the introduction of the polymerase chain reaction by Nobelist Kary Mullis and other scientists with the former Cetus Corp. in 1985, researchers can amplify their minute samples into a virtually unlimited supply of material to study.
Monoclonal Antibodies Find Utility In Cell Biology
Ricki Lewis | Dec 11, 1994 | 10+ min read
But, just as antibodies are finding increasing utility in cell biology, a new Food and Drug Administration classification for those products with clinical utility may affect researchers' access to the important technology (see accompanying story). Monoclonal History MAbs were born in 1975, when Georges Kohler and Cesar Milstein at the Medical Research Council Laboratories in Cambridge, England, fused two types of cells to form a hy

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