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tag stem cell trials developmental biology microbiology genetics genomics

Stem Cell Trial for Eye Disease Commences
Jef Akst | Sep 12, 2014 | 2 min read
Researchers at the RIKEN Center for Developmental Biology will treat the first patient in its clinical trial testing an induced pluripotent stem cell-based treatment for age-related macular degeneration.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Exploring the Past, Present, and Future of Brain Organoids 
Niki Spahich, PhD | Feb 18, 2024 | 5 min read
Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.
Stem Cells Made Waves in Biology and Medicine
Karen Zusi | Oct 1, 2016 | 6 min read
Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
poliovirus nprv2 vaccine-derived polio reversion virulence 481a mutation genetic engineering
New Oral Polio Vaccine to Bypass Key Clinical Trials
Robert Fortner | Dec 17, 2019 | 6 min read
Health officials are rushing a genetically engineered product into the field to counter uncontained outbreaks of vaccine-derived polio.
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
Stem Cell Discoveries Stir Debate
Douglas Steinberg | Nov 12, 2000 | 9 min read
Editor's Note: This is the first of two articles on questions raised by recent stem cell discoveries. The second article, focusing on various organs and the nervous system, will appear in the Nov. 27 issue of The Scientist. Researchers first isolated embryonic stem cells (ESCs) from mouse blastocysts almost 20 years ago, and a paper announcing the discovery of human ESCs emerged in 1998. Adult-derived stem cells (ASCs) have since become the rage in certain quarters of biology, with unexpected--

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