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tag transcription factors ecology cell molecular biology genetics genomics

Individual bacterial transcriptomes each plotted as a single point create a ring-shaped structure.
Rapidly Dividing Bacteria Coordinate Gene Expression and Replication
Kamal Nahas, PhD | Mar 15, 2024 | 4 min read
E. coli divides faster than it can replicate its genome, while simultaneously expressing its genes. Scientists recently revealed the intricate molecular coordination that makes this possible.
A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
Conceptual image of gene expression in DNA
Enhancers: Conserved in Activity, Not in Sequence
Jack J. Lee | Nov 1, 2021 | 8 min read
Certain stretches of DNA that regulate gene expression have evolved differently from protein-coding genes.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Transcription factors link rhizobia, legumes
Ishani Ganguli(iganguli@the-scientist.com) | Jun 19, 2005 | 3 min read
GRAS family proteins found to regulate nodules where nitrogen-fixing bacteria live
Context Is Key: Unlocking Tissue Complexity with Spatial Biology
Context Is Key: Unlocking Tissue Complexity with Spatial Biology
Deanna MacNeil, PhD | Mar 13, 2023 | 4 min read
Scientists combine spatially resolved imaging analyses with cutting edge single cell techniques for greater insight into fundamental and disease relevant pathways.
Layered visual representation of multiomics
Integrate and Innovate with NGS and Multiomics
The Scientist and Illumina | May 4, 2023 | 6 min read
Researchers across disciplines combine layers of discovery obtained with accessible NGS-based multiomics approaches.

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