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tag transcription factors genetics genomics culture evolution

A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
A black and brown ant stands over various sizes of whitish purple, oval shaped larvae and yellow, oblong eggs
A Single Transcription Factor Changes Ants to Queens
Abby Olena, PhD | Nov 5, 2021 | 3 min read
The transcription factor can also drive the opposite transition depending on which hormone activates it, according to a new study.
Yeast Made to Harvest Light Hint at Evolution’s Past
Kamal Nahas, PhD | Feb 21, 2024 | 6 min read
Scientists transferred light-harvesting proteins into yeast for the first time, shining a light on the past lives of eukaryotic cells.
Transcription factors help distinguish humans
Melissa Lee Phillips | Mar 8, 2006 | 3 min read
Most gene expression is under stabilizing selection in primates, but humans show directional evolution of regulatory genes
A taskmaster transcription factor
Elie Dolgin | Jun 28, 2009 | 2 min read
A scattered array of DNA acquired via horizontal transfer can co-evolve into a well-tuned, efficient genetic network to maximize an organism's fitness, a new linkurl:study;http://www.nature.com/msb/journal/v5/n1/full/msb200940.html finds. Reporting online earlier this month in __Molecular Systems Biology__, researchers showed that a single transcription factor in a tiny, salt-loving archaeon coordinates the expression of more than 100 newly-obtained genes. Halobacterium salinarumImage: Wikimedi
Organisms from infographic about transposable elements
Infographic: How Transposable Elements Can Shape Evolution
Christie Wilcox, PhD | Jan 17, 2022 | 2 min read
The movements of so-called jumping genes can generate the genetic diversity needed to drive evolutionary change in populations over time.  
Conceptual image of gene expression in DNA
Enhancers: Conserved in Activity, Not in Sequence
Jack J. Lee | Nov 1, 2021 | 8 min read
Certain stretches of DNA that regulate gene expression have evolved differently from protein-coding genes.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.

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