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tag cis regulatory elements ecology

The Genetics of Society
Claire Asher and Seirian Sumner | Jan 1, 2015 | 10 min read
Researchers aim to unravel the molecular mechanisms by which a single genotype gives rise to diverse castes in eusocial organisms.
Bioremediation: Cleaning Up With Biology And Technology
Angela Martello | Jan 6, 1991 | 7 min read
As the necessity of cleaning up the environment moves to the forefront of the public's consciousness, researchers in increasing numbers have been enlisting some of the earth's tiniest creatures to help clean up highly polluted sites and reclaim soils and groundwater systems. Stimulated by advances in microbiology and biotechnology, the booming multidisciplinary field of environmental biotechnology focuses on the use of microorganisms to treat or degrade hazardous waste, encompassing the techniq
Pufferfish Genomes Probe Human Genes
Ricki Lewis | Mar 17, 2002 | 7 min read
It may be humbling to think that humans have much in common with pufferfish, but at the genome level, the two are practically kissing cousins. "In terms of gene complement, we are at least 90% similar—probably higher. There are big differences in gene expression levels and alternate transcripts, but if you're talking about diversity, number and types of proteins, then it's pretty difficult to tell us apart," says Greg Elgar, group leader of the Fugu genome project at the Medical Research C
Finding a Mate
Barbara Cunningham | Apr 1, 2001 | 9 min read
Available Two-hybrid Systems Graphic: Leza BerardoneGenome sequencing has produced a vast supply of proteins in need of a functional identity. One way to identify a protein's function is to identify its interacting partners, because proteins often work in pairs or as part of large complexes. Scientists traditionally have used biophysical or biochemical methods (such as affinity chromatography or co-immunoprecipitation) to study protein-protein interactions. More recently, two-hybrid and phage-d
Choosing the Best Reporter Assay
Hillary Sussman | Jul 22, 2001 | 10+ min read
Suppliers of Reporter Assay Screening Systems Courtesy of Applied BiosystemsTarget practice: Researchers can employ reporter assays to study a variety of cellular processes. Rarely is the product of a gene readily distinguishable from the myriad mRNA and protein complements that exist in a cell at any point in time. But researchers can skirt this obstacle by placing a "reporter gene" under the same controls as the gene of interest. Reporter genes have easily measurable phenotypes that form th

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