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tag toxicity neuroscience disease medicine

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
illustration of brain cells in blue with amyloid plaques in orange and pink immune cells
Excerpt from The Memory Thief
Lauren Aguirre | Jun 1, 2021 | 10+ min read
Author Lauren Aguirre finds reasons for optimism in the fight against Alzheimer’s disease.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Image of brain cells showing pyramidal neurons in green, astrocytes in red, and microglia in blue
Replacing Microglia Treats Neurodegenerative Disease in Mice
Shawna Williams | Mar 17, 2022 | 2 min read
Researchers find a way to wipe out the brain’s immune cell corps and send in new and improved versions.
Microscopy image of a fluorescent green oligodendrocyte surrounded by astrocytes stained red with blue nuclei.
Searching for a Direct Route to Multiple Sclerosis Treatment
Deanna MacNeil, PhD | Jul 17, 2023 | 3 min read
Researchers created a new high-throughput tool to hunt for therapies that remyelinate the nervous system.
Opinion: Toxicants and the Brain
Philippe Grandjean | Jun 17, 2013 | 3 min read
Investment in brain research should aim at protecting the brains of the future from harmful environmental pollutants.
Brain cell in purple on a black background. Arc mRNAs are labeled green and are mainly localized in the cell nucleus and in the dendrites.
Short-lived Molecules Support Long-term Memory 
Alejandra Manjarrez, PhD | Jun 6, 2023 | 3 min read
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.
Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.
Yeast Models Provide New Insights into Neurodegenerative Diseases
Mahlon Collins | Oct 1, 2021 | 10+ min read
The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.

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