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tag sequence alignments genetics genomics evolution

The Evolution of Bats’ Super Immunity
Niki Spahich, PhD | Jan 10, 2024 | 4 min read
Researchers generated complete genomes of two important bat species and explored their immune- and cancer-related genes.
A close up of a tick held in a pair of forceps, with Kevin Esvelt’s face out of focus in the background.
CRISPR Gene Drives and the Future of Evolution
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.
Illustration showing assembly Versus Alignment
Infographic: The Sequencing and Assembly of the Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 5 min read
With ever-advancing genetic technologies, researchers continue to document the genetic code of the human species.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Conceptual image of gene expression in DNA
Enhancers: Conserved in Activity, Not in Sequence
Jack J. Lee | Nov 1, 2021 | 8 min read
Certain stretches of DNA that regulate gene expression have evolved differently from protein-coding genes.
Genome Digest
Cristina Luiggi | Mar 7, 2012 | 3 min read
Meet the species whose DNA has recently been sequenced.
An Edith’s checkerspot butterfly
Genome Spotlight: Edith’s Checkerspot Butterfly (Euphydryas editha)
Christie Wilcox, PhD | Aug 25, 2022 | 3 min read
A high-quality genome sequence for this versatile insect will likely aid eco-evolutionary research.
Targeted Comparative Sequencing Illuminates Vertebrate Evolution
Ricki Lewis | Dec 8, 2002 | 6 min read
Image: Courtesy of Elliott Marguiles  PIPS ON PARADE: Researchers used a MultiPipMaker to show the alignments, expressed as percent identity plots, between a human reference sequence and several other species. This is a 20 kb region surrounding exon 2 of the MET gene. Gap-free alignable segments are represented as horizontal lines along the human reference sequence; the line's height represents the identity of that alignment. Aristotle envisioned humanity as the pinnacle of a "Great Chai
Photo of a North American caribou (Rangifer tarandus) in Jasper National Park in Canada
Dozens of Genes Tied to Caribou’s Seasonal Migration
Maddie Bender | May 2, 2022 | 2 min read
Researchers tracked the movements of endangered caribou and sequenced a portion of their genomes to determine which genes may influence migratory behavior.

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