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image: Top Technical Advances in 2017

Top Technical Advances in 2017

By Shawna Williams | December 25, 2017

The year’s most impressive achievements include new methods to extend CRISPR editing, patch-clamp neurons hands-free, and analyze the contents of live cells.

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image: CRISPR Helps Mice Hear

CRISPR Helps Mice Hear

By Abby Olena | December 20, 2017

Researchers reduce the severity of hereditary deafness in mice with the delivery of CRISPR-Cas9 protein-RNA complexes that inactivate a mutant gene in their inner ears. 

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image: Hibernating Rodents Feel Less Cold

Hibernating Rodents Feel Less Cold

By Abby Olena | December 19, 2017

Syrian hamsters and thirteen-lined ground squirrels are tolerant of chilly temperatures, thanks to amino acid changes in a cold-responsive ion channel. 

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Upping a gene’s expression in rat brains made them better learners and normalized the activity of hundreds of other genes to resemble the brains of younger animals.

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image: New Resource Ranks Chemical Probes for Human Proteins

New Resource Ranks Chemical Probes for Human Proteins

By Abby Olena | December 14, 2017

With many probes being seriously flawed, Probe Miner helps researchers find those that are most specific and effective for manipulating their chosen proteins.

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Single-cell genome analyses reveal the amount of mutations a human brain cell will collect from its fetal beginnings until death.

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image: Book Excerpt from <em>Jane on the Brain</em>

Book Excerpt from Jane on the Brain

By Wendy Jones | December 1, 2017

In chapter 3, “The Sense of Sensibility,” author Wendy Jones uses scenes from one of Jane Austen’s most celebrated novels to illustrate the functioning of the body’s stress response system.

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Aggressive little marine predators, mantis shrimps possess a mushroom body that appears identical to the one found in insects.

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image: Optical Cell Sorting

Optical Cell Sorting

By Rachel Berkowitz | December 1, 2017

Researchers are using light and new image processing tools for label-free cell characterization.

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image: Sense, Sensibility, and Neuroscience

Sense, Sensibility, and Neuroscience

By Wendy Jones | December 1, 2017

Jane Austen can teach us a lot about how our brains handle uncertainty.

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