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image: Targeting Tregs Halts Cancer’s Immune Helpers

Targeting Tregs Halts Cancer’s Immune Helpers

By | April 1, 2017

New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture.

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image: Anti-Flavivirus Antibodies Enhance Zika Infection in Mice

Anti-Flavivirus Antibodies Enhance Zika Infection in Mice

By | March 30, 2017

Researchers report evidence of antibody-dependent enhancement in a Zika-infected, immunocompromised mouse model.

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image: Experimental MERS Treatments Target Host Cell Receptor

Experimental MERS Treatments Target Host Cell Receptor

By | March 30, 2017

Researchers are searching for ways to prevent the coronavirus from attaching to DPP-4 receptors, blocking it from invading and replicating within host cells.

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image: Massively Parallel Perturbations

Massively Parallel Perturbations

By | March 1, 2017

Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.

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image: Infographic: Single-Cell CRISPR Screens

Infographic: Single-Cell CRISPR Screens

By | March 1, 2017

See how two new methods track responses to unique genetic manipulations in numerous individual cells in parallel.

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image: Broad Wins CRISPR Patent Interference Case

Broad Wins CRISPR Patent Interference Case

By | February 15, 2017

The USPTO’s Patent Trial and Appeal Board has ruled in favor of the Broad Institute of MIT and Harvard retaining intellectual property rights covered by its patents for CRISPR gene-editing technology.

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image: Deep Pocket Exploration

Deep Pocket Exploration

By | February 1, 2017

A modification to traditional docking software enables the examination of a ligand’s passage into its receptor.

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image: Discovering Novel Antibiotics

Discovering Novel Antibiotics

By | February 1, 2017

Three methods identify and activate silent bacterial gene clusters to uncover new drugs

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image: Infographic: Modeling Molecules’ Receptor Binding

Infographic: Modeling Molecules’ Receptor Binding

By | February 1, 2017

A software upgrade follows ligands step-wise into their binding sites on receptors.

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image: Unique Antibodies Open Path Toward New HIV Vaccines

Unique Antibodies Open Path Toward New HIV Vaccines

By | January 27, 2017

A family of broadly neutralizing antibodies from a chronically infected donor provides a schematic for designing vaccines and treatments that target multiple strains of the virus.

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