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image: Infographic: Breaking into the Brain

Infographic: Breaking into the Brain

By | November 1, 2017

The blood-brain barrier is a collection of specialized cells and proteins that control the movement of molecules from the blood to the central nervous system.

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image: Getting Drugs Past the Blood-Brain Barrier

Getting Drugs Past the Blood-Brain Barrier

By | November 1, 2017

To treat neurological disease, researchers develop techniques to bypass or trick the guardian of the central nervous system.

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Research in human patients and mice reveals the role of the circadian clock in the risk of heart damage at different times of day.

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With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.

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image: FDA Approves Second CAR T-Cell Therapy

FDA Approves Second CAR T-Cell Therapy

By | October 19, 2017

The therapy, produced by Kite Pharma and owned by Gilead Sciences, is approved for use against some types of large B-cell lymphomas. 

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image: Compound Found in Red Wine Boosts Immune Cell Function

Compound Found in Red Wine Boosts Immune Cell Function

By | October 17, 2017

At low doses, resveratrol enhanced human T-cell activity in vitro, while at high doses it interfered with cell signaling. 

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image: Cancers Relapse by Feeding Off Immune Signals

Cancers Relapse by Feeding Off Immune Signals

By | October 16, 2017

In mice, the tumor cells are able to thwart the immune response that would kill them—but immunotherapy prevented the return of melanoma.

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Chemistry Nobel goes to Jacques Dubochet, Joachim Frank, and Richard Henderson. 

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image: Image of the Day: Fragile Brain

Image of the Day: Fragile Brain

By | October 3, 2017

In Fragile X syndrome—a genetic mishap that results in cognitive delays—the lack of a translation-repressing protein leads to the rampant accumulation of other proteins in the mouse brain.

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image: Nonviral CRISPR Delivery a Success

Nonviral CRISPR Delivery a Success

By | October 2, 2017

Researchers use gold nanoparticles to deliver CRISPR-Cas9 and correct a point mutation in a mouse model of Duchenne muscular dystrophy. 

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  4. Research Links Gut Health to Neurodegeneration
    The Nutshell Research Links Gut Health to Neurodegeneration

    Rodent studies presented at the Society for Neuroscience meeting this week tie pathologies in the gastrointestinal tract or microbiome composition with Parkinson’s and Alzheimer’s diseases.

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