techniques

Choosing the right model, be it 3-D or 2-D, requires wading through varied cell sources, cell types, and cell culture conditions.

A bacteriophage must evolve certain variants of a protein or die.

The Broad Institute and Rockefeller University disagree over which scientists should be named as inventors on certain patents involving the gene-editing technology.

“Ultimate DISCO” uses a solvent that shrinks whole animals and preserves fluorescence for months.

A former researcher at the Broad Institute has suggested the University of California, Berkeley, team deserves credit for inventing the gene-editing technique.

Researchers use the CRISPR/Cas system to express three transcription-factor genes, changing the identities of mouse cells.

Researchers have designed a screen to find unique molecules, called riboswitches, that determine whether transcription will proceed.

Profiles of five programs for quantifying data from Westerns, dot blots, gels, and colony cultures

A point-and-click interface alternative to command-line tools that allows researchers to easily create, run, and troubleshoot serial sequence analyses

A newly developed method detects regulators of bacterial transcription called riboswitches.

The catalytic domain of an RNA-editing enzyme is fused with RNA-binding proteins.

Techniques for determining which genes or genetic variants are truly detrimental

There’s a right way and a wrong way to boost the statistical sensitivity of this type of clinical studies.

Researchers are developing potent ways to fuel and control the movement of micromotor devices.

Using proteomics methods to inform antigen selection

Lacing insect food with microbes encoding double-stranded RNAs can suppress insect gene expression.

Researchers mix bacteria genetically engineered to express double-stranded RNA into insect food.

A versatile modular strategy for detecting small molecules in eukaryotes

Tips for tracing transcription in individual cells

Techniques for deep dives into the microbial dark matter