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image: New and Old Techniques in Modern Neuroscience

New and Old Techniques in Modern Neuroscience

By | October 1, 2016

Imaging and manipulating the brain has come a long way from electrodes and the patch clamp, though such traditional tools remain essential.

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image: Stem Cells Made Waves in Biology and Medicine

Stem Cells Made Waves in Biology and Medicine

By | October 1, 2016

Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.

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image: Thirty Years of Progress

Thirty Years of Progress

By | October 1, 2016

Since The Scientist published its first issue in October 1986, life-science research has transformed from a manual and often tedious task to a high-tech, largely automated process of unprecedented efficiency.

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image: Toggling CRISPR Activity with a Chemical Switch

Toggling CRISPR Activity with a Chemical Switch

By | September 12, 2016

Researchers design a Cas9 enzyme that cuts DNA only in the presence of particular drug.

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image: Group Proposes Strategies to Improve Antibodies

Group Proposes Strategies to Improve Antibodies

By | September 5, 2016

An expert committee encourages reagent providers to adopt one of five methods to validate products.

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image: The History of Optogenetics Revised

The History of Optogenetics Revised

By | September 1, 2016

Credit for the neuroscience technique has largely overlooked the researcher who first demonstrated the method.

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image: Designing In Vitro Models of the Blood-Brain Barrier

Designing In Vitro Models of the Blood-Brain Barrier

By | September 1, 2016

Choosing the right model, be it 3-D or 2-D, requires wading through varied cell sources, cell types, and cell culture conditions.

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image: Promoting Protein Partnerships

Promoting Protein Partnerships

By | September 1, 2016

Scientists generate new protein-protein interactions at an impressive PACE.

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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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image: Protein or Perish

Protein or Perish

By | September 1, 2016

A bacteriophage must evolve certain variants of a protein or die.

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