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The findings more than double the number of known defense mechanisms, piquing the interests of molecular biology tool developers.

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image: CRISPR Trial for Cancer Patients Proposed

CRISPR Trial for Cancer Patients Proposed

By Katarina Zimmer | January 19, 2018

US researchers could become the first outside China to use the gene-editing technique in the clinic. 

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The discovery reveals the role of a growth factor and endothelial cells in thymus repair, and could have implications for chemotherapy and radiation patients’ recovery following treatment.

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The BMJ inquiry finds that researchers presented only select results from animal experiments when applying for funding and approval for human trials.

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image: Maternal Response to Zika Damages Mouse Fetuses

Maternal Response to Zika Damages Mouse Fetuses

By Catherine Offord | January 5, 2018

Signaling pathways triggered by the mother’s immune system may cause complications during fetal development.

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image: Alcohol Damages Mouse DNA

Alcohol Damages Mouse DNA

By Jef Akst | January 3, 2018

A byproduct of alcohol consumption causes mutations in the DNA of mouse blood stem cells, and some of the breaks are not repaired.

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image: Glial Ties to Persistent Pain

Glial Ties to Persistent Pain

By Mark R. Hutchinson | January 1, 2018

Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.

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image: Infographic: A Painful Pathway

Infographic: A Painful Pathway

By Catherine Offord | January 1, 2018

Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.

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image: Infographic: Two Pain Paths Diverge in the Body

Infographic: Two Pain Paths Diverge in the Body

By Mark R. Hutchinson | January 1, 2018

The acute pain that results from injury or disease is very different from chronic pain.

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image: Targeting Sodium Channels for Pain Relief

Targeting Sodium Channels for Pain Relief

By Catherine Offord | January 1, 2018

The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.

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