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tag chronic pain neuroscience culture cell molecular biology

Resolving Chronic Pain
Claudia Sommer and Frank Birklein | Jan 1, 2012 | 10+ min read
The body’s own mechanism for dispersing the inflammatory reaction might lead to new treatments for chronic pain.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Image of someone scratching their skin.
A Chronic Itch: Burrowing Beneath the Skin
Brian S. Kim, MD | Sep 8, 2023 | 9 min read
We have barely scratched the surface of itch science and what it indicates about our health.
David Julius Probes the Molecular Mechanics of Pain
Anna Azvolinsky | Jan 1, 2018 | 8 min read
For nearly 30 years, the UC San Francisco researcher has delved into unexplored corners of the nervous system.
Glial Ties to Persistent Pain
Mark R. Hutchinson | Jan 1, 2018 | 10 min read
Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Photograph of a mouse covering his face with his paw.
Bless You: Mouse Model Reveals Molecular Pathway Behind Sneezing
Amanda Heidt | Oct 1, 2021 | 3 min read
Researchers have identified specific cells and neuropeptides involved in mediating the sneeze response in mice exposed to allergens or chemical irritants such as capsaicin.
sketch of two men smiling
Mechanisms of Chili’s Heat, Menthol’s Cool Garner Nobel
Chloe Tenn | Oct 4, 2021 | 4 min read
David Julius and Ardem Patapoutian won this year’s Nobel Prize in Physiology or Medicine for their research on the ion channels involved in perceiving heat, cold, pain, and touch.
Getting at the Molecular Roots of Pain
Karen Hopkin | Jan 3, 1999 | 8 min read
to eliminate difficult-to-control pain while leaving normal sensation intact. Pain is a part of life. Often, a few painkillers and some rest are enough to soothe the scraped knees of childhood and the aches and sprains of adulthood. But for some, pain is not as fleeting or as easily dismissed. The pain from cancer, chemotherapy, arthritis, AIDS, and other diseases can be unrelenting and incapacitating. Some individuals even experience constant, bone-crushing pain for no apparent reason. For man
Targeting Sodium Channels for Pain Relief
Catherine Offord | Jan 1, 2018 | 10+ min read
The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.

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