Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.
Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.
An experimental technique removes T cells that aid in vitro tumor growth.
Neoantigens may serve as valuable targets for new immunotherapies.
New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture.
Researchers report evidence of antibody-dependent enhancement in a Zika-infected, immunocompromised mouse model.
Researchers are searching for ways to prevent the coronavirus from attaching to DPP-4 receptors, blocking it from invading and replicating within host cells.
Murine neural tubes, with each image highlighting a different embryonic tissue type (blue). The neural tube itself (left) grows into the brain, spine, and nerves, while the mesoderm (middle) develops into other organs, and the ectoderm (right) forms skin, teeth, and hair.
Academics partner with a biotech firm to investigate cannabinoids and develop potential therapeutics.
Researchers report growing a mouse embryo using two types of early stem cells.
The nationwide experiment will initially include around 100,000 volunteers.
After implantation, the tissue developed blood vessels and became integrated into neuronal networks in the animals’ brains.
A preliminary clinical trial finds that the personalized therapy improves survival rates and has no severe side-effects.
Many cities around the globe, including Washington, DC, saw shrunken crowd sizes, and numerous events turned into rallies rather than processions.
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