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» chronic pain, ecology and immunology

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image: Infographic: A Painful Pathway

Infographic: A Painful Pathway

By Catherine Offord | January 1, 2018

Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.

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image: Infographic: Two Pain Paths Diverge in the Body

Infographic: Two Pain Paths Diverge in the Body

By Mark R. Hutchinson | January 1, 2018

The acute pain that results from injury or disease is very different from chronic pain.

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image: Painful Realities

Painful Realities

By The Scientist Staff | January 1, 2018

Dave Thomas, a researcher at the National Institute on Drug Abuse, talks about the harsh truths and frustrating complexity of pain and analgesia.

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image: Prizes and Penalties

Prizes and Penalties

By Bob Grant | January 1, 2018

Life is filled with pleasure and pain. Science and society are struggling mightily with both.

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image: Targeting Sodium Channels for Pain Relief

Targeting Sodium Channels for Pain Relief

By Catherine Offord | January 1, 2018

The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.

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image: Antiviral Immunotherapy Comes of Age

Antiviral Immunotherapy Comes of Age

By Lucas Laursen | December 4, 2017

T-cell therapies are not just for cancer. Researchers are also advancing immunotherapy methods to protect bone marrow transplant patients from viral infections. 

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A single receptor on natural killer cells recognizes an amino acid sequence conserved across Zika, dengue, and related pathogens.

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image: European Research Council Founder, Molecular Biologist Dies

European Research Council Founder, Molecular Biologist Dies

By Catherine Offord | November 20, 2017

Fotis Kafatos, a Greek researcher famous for his work on malaria, has died at age 77.

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image: Optogenetic Therapies Move Closer to Clinical Use

Optogenetic Therapies Move Closer to Clinical Use

By Shawna Williams | November 16, 2017

With a clinical trial underway to restore vision optogenetically, researchers also see promise in using the technique to treat deafness, pain, and other conditions.

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A team has engineered two stem cell lines into “synthetic T cells” that destroy breast cancer cells in vitro. 

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