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tag chronic pain evolution disease medicine developmental biology

Image of someone scratching their skin.
A Chronic Itch: Burrowing Beneath the Skin
Brian S. Kim, MD | Sep 8, 2023 | 9 min read
We have barely scratched the surface of itch science and what it indicates about our health.
3d rendered medically accurate illustration of a human embryo anatomy
The Ephemeral Life of the Placenta
Danielle Gerhard, PhD | Dec 4, 2023 | 10+ min read
Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.
The Science of Stretch
Helene M. Langevin | May 1, 2013 | 10 min read
The study of connective tissue is shedding light on pain and providing new explanations for alternative medicine.
The Little Cell That Could
Megan Scudellari | Jul 1, 2012 | 7 min read
Critics point out that cell therapy has yet to top existing treatments. Biotech companies are setting out to change that—and prove that the technology can revolutionize medicine.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Optogenetic Therapies Move Closer to Clinical Use
Shawna Williams | Nov 16, 2017 | 6 min read
With a clinical trial underway to restore vision optogenetically, researchers also see promise in using the technique to treat deafness, pain, and other conditions.
Can Destroying Senescent Cells Treat Age-Related Disease?
Katarina Zimmer | Mar 1, 2020 | 10+ min read
A handful of clinical trials are underway to find out whether drugs that target senescent cells can slow the ravages of old age.
AIDS Pandemic Provokes Alarming Reassessments Of Infectious Disease
Joshua Lederberg | Jul 11, 1993 | 5 min read
In 1900, infectious disease was the leading cause of mortality in the United States, accounting for at least 37 percent of deaths. By 1950, this had been mitigated to 6.8 percent and, by 1989, to 2.8 percent, with corresponding improvements in life expectancy. These numbers, of course, must be taken with a grain of salt, given the eventual preemptive role of infection in chronic illness, and many disorders whose infectious etiology is still to be recognized. Further, the relative importance
Better Mouse Memory Comes at a Price
Deborah Stull | Apr 1, 2001 | 2 min read
Researchers have discovered that transgenic mice previously shown to outperform their normal counterparts on learning and memory tests1 are also more sensitive to chronic pain.2 This finding suggests that memory formation and pain sensation might share components of a common physiological pathway in mice, and therefore, possibly in other vertebrates such as humans. These "Doogie" mice (scientifically manipulated mice that make more than the usual amount of the NR2B subunit of the NMDA [N-methy
Conceptual image showing fragmented X chromosomes
How Chaos in Chromosomes Helps Drive Cancer Spread
Samuel F. Bakhoum | Mar 1, 2022 | 10+ min read
A new link between inflammation and rampant chromosomal abnormalities reveals novel strategies to treat diverse malignancies.

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