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image: Glial Ties to Persistent Pain

Glial Ties to Persistent Pain

By Mark R. Hutchinson | January 1, 2018

Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.

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image: Infographic: A Painful Pathway

Infographic: A Painful Pathway

By Catherine Offord | January 1, 2018

Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.

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image: Infographic: Two Pain Paths Diverge in the Body

Infographic: Two Pain Paths Diverge in the Body

By Mark R. Hutchinson | January 1, 2018

The acute pain that results from injury or disease is very different from chronic pain.

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image: Painful Realities

Painful Realities

By The Scientist Staff | January 1, 2018

Dave Thomas, a researcher at the National Institute on Drug Abuse, talks about the harsh truths and frustrating complexity of pain and analgesia.

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image: Prizes and Penalties

Prizes and Penalties

By Bob Grant | January 1, 2018

Life is filled with pleasure and pain. Science and society are struggling mightily with both.

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image: Swearing Off Pain

Swearing Off Pain

By The Scientist Staff | January 1, 2018

Author Emma Byrne runs down the benefits of cursing, among them an enhanced ability to withstand pain.

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image: Targeting Sodium Channels for Pain Relief

Targeting Sodium Channels for Pain Relief

By Catherine Offord | January 1, 2018

The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.

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image: Ten-Minute Sabbatical

Ten-Minute Sabbatical

By The Scientist Staff | January 1, 2018

Take a break from the bench to puzzle and peruse.

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image: Why Swearing and Pain Go Hand in Hand

Why Swearing and Pain Go Hand in Hand

By Emma Byrne | January 1, 2018

Screaming obscenities when you stub your toe makes perfect biological sense.

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image: Hibernating Rodents Feel Less Cold

Hibernating Rodents Feel Less Cold

By Abby Olena | December 19, 2017

Syrian hamsters and thirteen-lined ground squirrels are tolerant of chilly temperatures, thanks to amino acid changes in a cold-responsive ion channel. 

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