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image: New Insights to Improve CAR T Cells’ Safety

New Insights to Improve CAR T Cells’ Safety

By Vicki Brower | June 5, 2018

Drugs approved to treat rheumatoid arthritis block cytokines, the molecules responsible for severe side effects from the immunotherapy, and reduce symptoms in mice.

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Luna DNA, Nebula Genomics, and other “bio-brokers” will allow customers to make money by granting access to their genetic and personal information for research purposes.

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image: A T-Cell Tweak Combats Advanced Breast Cancer

A T-Cell Tweak Combats Advanced Breast Cancer

By Ashley Yeager | June 5, 2018

The immunotherapy eliminated a woman’s metastatic lesions and kept her disease-free for two years.

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image: Immunotherapy Drug Shows Promise for Melanoma, Lung Cancer

Immunotherapy Drug Shows Promise for Melanoma, Lung Cancer

By Sukanya Charuchandra | June 4, 2018

Merck’s Keytruda extended the lives of lung cancer patients by several months and appeared to stop the progression of advanced melanoma.  

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image: Condensin Folds DNA Through Loop Extrusion

Condensin Folds DNA Through Loop Extrusion

By Diana Kwon | June 1, 2018

By observing the activity of a protein complex in real time, researchers have uncovered new evidence for a long-standing theory.

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image: Contributors

Contributors

By Jim Daley | June 1, 2018

Meet some of the people featured in the June 2018 issue of The Scientist.

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image: Infographic: Caveolae Form and Function

Infographic: Caveolae Form and Function

By Ben Nichols | June 1, 2018

Researchers interrogate the cavernous structures on the surface of cells to better understand how they affect membrane function.

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An entrepreneurial attitude helped this Vienna-based researcher begin to unravel the complex receptor network that Arabidopsis uses to  develop and defend itself.

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image: Infographic: Packing DNA

Infographic: Packing DNA

By Diana Kwon | June 1, 2018

Researchers watch the protein condensin in action.

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image: New Technologies Shed Light on Caveolae

New Technologies Shed Light on Caveolae

By Ben Nichols | June 1, 2018

The functions of the cellular invaginations identified more than half a century ago are now beginning to be understood in detail.

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