mouse research

Many researchers have stopped breeding mice, reduced the size of colonies, and established contingency plans in case animal care staff get sick.

In mice, a group of nasal epithelial cells called brush cells release pro-inflammatory signals in response to allergens.

Recent work in humans and mice highlights how exposure to environmental microbes helps protect against allergies and other inflammatory diseases.

Researchers find strains of the bacterium Klebsiella pneumoniae that produce high levels of alcohol in 60 percent of patients with the condition.

Curbing the growth of harmful bacteria in mouse microbiomes reduces the animals’ incidence of inflammation-related colorectal cancer.

Neither the maternal microbiome nor housing conditions appear to permanently alter which microbes remain in the animals.

Detailed imaging of the rodent central nervous system reveals new information about the route cerebrospinal fluid takes to leave the brain.

Staff at the UK’s Harwell Institute were notified that a strategy board recommended halting its academic work, but a final decision is months away.

When hair follicle stem cells lose their protein-based death cue, they take on a new role helping to repair wounds in skin.

T cells modified to target disease-contributing B cells improved survival in two mouse models of the autoimmune disease.

Researchers develop an app that can estimate the biological age of a rodent from its mug shot—and could give a boost to the science of human aging in the process.

Genetic mutations create lab mice with unusually long and short tails.

Researchers use a CRISPR-Cas9 strategy to expand a desired trait from 50 percent of mouse pups to about 72 percent.

A mesh records retinal cells’ firings in live animals.

The bipaternal pups died soon after birth, but mice with two mothers grew into fertile adults.

Researchers from 17 labs report low efficacy rates for the popular technique.

The hybrid cells promote tumor heterogeneity and possible metastasis, a new study in mice and humans shows.

Researchers silence pain neurons in the mouse spinal cord with injections of botulinum toxins modified to bind to the neurons’ receptors.

By stimulating specific neurons in mouse brains, researchers demonstrate that memories from infancy are not lost, but merely difficult to access.