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image: Primary Cilia in Neurons Linked to Obesity

Primary Cilia in Neurons Linked to Obesity

By Abby Olena | January 8, 2018

Three studies—one of mice and two of human genetics—describe the role of two proteins, adenylyl cyclase and melanocortin 4 receptor, in the development of obesity and diabetes. 

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The company’s recent effort to find new treatments for Alzheimer’s ended in disappointment.

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image: Maternal Response to Zika Damages Mouse Fetuses

Maternal Response to Zika Damages Mouse Fetuses

By Catherine Offord | January 5, 2018

Signaling pathways triggered by the mother’s immune system may cause complications during fetal development.

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image: Alcohol Damages Mouse DNA

Alcohol Damages Mouse DNA

By Jef Akst | January 3, 2018

A byproduct of alcohol consumption causes mutations in the DNA of mouse blood stem cells, and some of the breaks are not repaired.

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image: Annina Schmid Dissects Nerve Disorders

Annina Schmid Dissects Nerve Disorders

By Catherine Offord | January 1, 2018

A background in physiotherapy helps the Oxford-based researcher mix basic science with clinical work to better understand pain stemming from nerve compression.

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image: Contributors

Contributors

By Jef Akst and Katarina Zimmer | January 1, 2018

Meet some of the people featured in the January 2018 issue of The Scientist.

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image: Distinct Regions Drive Responses to Anxiety, Fear

Distinct Regions Drive Responses to Anxiety, Fear

By Catherine Offord | January 1, 2018

Researchers map brain activity associated with a person’s anticipation of or direct confrontation with danger.

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image: Glial Ties to Persistent Pain

Glial Ties to Persistent Pain

By Mark R. Hutchinson | January 1, 2018

Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.

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image: Infographic: A Painful Pathway

Infographic: A Painful Pathway

By Catherine Offord | January 1, 2018

Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.

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image: Infographic: Anticipation Versus Confrontation

Infographic: Anticipation Versus Confrontation

By Catherine Offord | January 1, 2018

The brain is activated differently when it’s contemplating, rather than directly facing, a threat.

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