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image: Neoantigens Enable Personalized Cancer Immunotherapy

Neoantigens Enable Personalized Cancer Immunotherapy

By Stephen P. Schoenberger and Ezra Cohen | April 1, 2017

Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.

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image: Infographic: Antibody Cancer Therapy

Infographic: Antibody Cancer Therapy

By Ruth Williams | April 1, 2017

An experimental technique removes T cells that aid in vitro tumor growth.

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image: Infographic: Targeting Cancer Antigens

Infographic: Targeting Cancer Antigens

By Stephen P. Schoenberger and Ezra Cohen | April 1, 2017

Neoantigens may serve as valuable targets for new immunotherapies.

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image: Targeting Tregs Halts Cancer’s Immune Helpers

Targeting Tregs Halts Cancer’s Immune Helpers

By Ruth Williams | April 1, 2017

New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture.

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image: Anti-Flavivirus Antibodies Enhance Zika Infection in Mice

Anti-Flavivirus Antibodies Enhance Zika Infection in Mice

By Anna Azvolinsky | March 30, 2017

Researchers report evidence of antibody-dependent enhancement in a Zika-infected, immunocompromised mouse model.

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image: Experimental MERS Treatments Target Host Cell Receptor

Experimental MERS Treatments Target Host Cell Receptor

By Ashley Yeager | March 30, 2017

Researchers are searching for ways to prevent the coronavirus from attaching to DPP-4 receptors, blocking it from invading and replicating within host cells.

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SP140, an epigenetic reader protein mutated in a number of autoimmune disorders, is essential for macrophage function and preventing intestinal inflammation, scientists show. 

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image: Unique Antibodies Open Path Toward New HIV Vaccines

Unique Antibodies Open Path Toward New HIV Vaccines

By Amanda B. Keener | January 27, 2017

A family of broadly neutralizing antibodies from a chronically infected donor provides a schematic for designing vaccines and treatments that target multiple strains of the virus.

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Study of 81 six-week-olds who were born by C-section or vaginal delivery didn’t show differences in the structure or function of their microbiota, despite contrary results from other studies on babies. 

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Person-to-person transmission of carbapenem-resistant Enterobacteriaceae in US hospitals may be occurring without symptoms, a new study suggests. 

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