Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.
Researchers are going beyond fecal samples to understand how the patterns of commensal microbes in the gastrointestinal tract influence development and health.
Carolyn A. Thomson and Kathy D. McCoy | Aug 1, 2021 | 10+ min read
Bacteria in the gut influence the production of antibodies and themselves secrete metabolites. In a pregnant woman, these compounds may influence immune development of her fetus.
Carolyn A. Thomson and Kathy D. McCoy | Aug 1, 2021 | 3 min read
Work in rodents shows that the bacteria living in a mother’s gut can produce immunomodulatory metabolites and influence the production of maternal antibodies—both of which can affect her offspring’s development.
Researchers identify live bacteria in fetal guts, skin, lungs, and placentas that activate memory T cells, indicating that early exposure to microbes could help educate the developing immune system.
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.